{"id":4411,"date":"2026-05-05T11:01:49","date_gmt":"2026-05-05T04:01:49","guid":{"rendered":"http:\/\/khcn185.vnua.edu.vn\/?p=4411"},"modified":"2026-05-06T11:03:12","modified_gmt":"2026-05-06T04:03:12","slug":"nghien-cuu-dac-diem-hinh-thai-va-cau-truc-vi-the-cua-buong-trung-va-ong-dan-trung-o-bo-sua-holstein-friesian-mac-benh-u-nang-buong-trung","status":"publish","type":"post","link":"http:\/\/khcn185.vnua.edu.vn\/?p=4411","title":{"rendered":"Nghi\u00ean c\u1ee9u \u0111\u1eb7c \u0111i\u1ec3m h\u00ecnh th\u00e1i v\u00e0 c\u1ea5u tr\u00fac vi th\u1ec3..."},"content":{"rendered":"\n\n<p style=\"text-align: justify;\">B\u00f2 s\u1eefa Holstein\u2013Friesian l\u00e0 gi\u1ed1ng b\u00f2 c\u00f3 n\u0103ng su\u1ea5t s\u1eefa cao, tuy nhi\u00ean th\u01b0\u1eddng g\u1eb7p c\u00e1c r\u1ed1i lo\u1ea1n sinh s\u1ea3n, trong \u0111\u00f3 b\u1ec7nh u nang bu\u1ed3ng tr\u1ee9ng l\u00e0 m\u1ed9t trong nh\u1eefng nguy\u00ean nh\u00e2n quan tr\u1ecdng g\u00e2y gi\u1ea3m kh\u1ea3 n\u0103ng sinh s\u1ea3n. Nh\u1eb1m l\u00e0m r\u00f5 c\u01a1 s\u1edf khoa h\u1ecdc c\u1ee7a b\u1ec7nh l\u00fd n\u00e0y, \u0111\u1ec1 t\u00e0i nghi\u00ean c\u1ee9u \u0111\u00e3 t\u1eadp trung ph\u00e2n t\u00edch \u0111\u1eb7c \u0111i\u1ec3m h\u00ecnh th\u00e1i v\u00e0 c\u1ea5u tr\u00fac vi th\u1ec3 c\u1ee7a bu\u1ed3ng tr\u1ee9ng v\u00e0 \u1ed1ng d\u1eabn tr\u1ee9ng, \u0111\u1ed3ng th\u1eddi \u0111\u00e1nh gi\u00e1 s\u1ef1 bi\u1ebfn \u0111\u1ed5i t\u1ebf b\u00e0o th\u1ec3 v\u00e0ng trong c\u00e1c giai \u0111o\u1ea1n ph\u00e1t tri\u1ec3n kh\u00e1c nhau.<\/p>\n<p style=\"text-align: justify;\">K\u1ebft qu\u1ea3 cho th\u1ea5y, ph\u1ec5u h\u1ee9ng tr\u1ee9ng (infundibulum) v\u00e0 b\u00f3ng \u1ed1ng d\u1eabn tr\u1ee9ng (ampulla) c\u00f3 s\u1ef1 bi\u1ebfn \u0111\u1ed5i r\u00f5 r\u1ec7t v\u1ec1 h\u00ecnh th\u00e1i v\u00e0 m\u00f4 h\u1ecdc gi\u1eefa c\u00e1c pha c\u1ee7a chu k\u1ef3 sinh d\u1ee5c. Trong \u0111i\u1ec1u ki\u1ec7n sinh l\u00fd b\u00ecnh th\u01b0\u1eddng, pha nang tr\u1ee9ng \u0111\u1eb7c tr\u01b0ng b\u1edfi s\u1ed1 l\u01b0\u1ee3ng n\u1ebfp g\u1ea5p ni\u00eam m\u1ea1c l\u1edbn, chi\u1ec1u d\u00e0i v\u00e0 \u0111\u1ed9 d\u00e0y n\u1ebfp g\u1ea5p t\u0103ng, bi\u1ec3u m\u00f4 cao v\u00e0 gi\u00e0u t\u1ebf b\u00e0o c\u00f3 l\u00f4ng chuy\u1ec3n, ph\u1ea3n \u00e1nh vai tr\u00f2 h\u1ed7 tr\u1ee3 b\u1eaft gi\u1eef v\u00e0 v\u1eadn chuy\u1ec3n no\u00e3n. Ng\u01b0\u1ee3c l\u1ea1i, pha th\u1ec3 v\u00e0ng ghi nh\u1eadn ho\u1ea1t \u0111\u1ed9ng ti\u1ebft t\u0103ng c\u01b0\u1eddng v\u1edbi s\u1ef1 hi\u1ec7n di\u1ec7n r\u00f5 c\u1ee7a c\u00e1c t\u1ebf b\u00e0o ti\u1ebft v\u00e0 ph\u1ea3n \u1ee9ng d\u01b0\u01a1ng t\u00ednh m\u1ea1nh v\u1edbi thu\u1ed1c nhu\u1ed9m PAS, ph\u00f9 h\u1ee3p v\u1edbi ch\u1ee9c n\u0103ng nu\u00f4i d\u01b0\u1ee1ng h\u1ee3p t\u1eed v\u00e0 h\u1ed7 tr\u1ee3 qu\u00e1 tr\u00ecnh th\u1ee5 tinh.<\/p>\n<p style=\"text-align: justify;\">Trong tr\u01b0\u1eddng h\u1ee3p b\u00f2 m\u1eafc b\u1ec7nh u nang bu\u1ed3ng tr\u1ee9ng, c\u1ea5u tr\u00fac \u1ed1ng d\u1eabn tr\u1ee9ng b\u1ecb suy gi\u1ea3m \u0111\u00e1ng k\u1ec3. S\u1ed1 l\u01b0\u1ee3ng v\u00e0 k\u00edch th\u01b0\u1edbc c\u00e1c n\u1ebfp g\u1ea5p ni\u00eam m\u1ea1c gi\u1ea3m, bi\u1ec3u m\u00f4 th\u1ea5p, s\u1ed1 l\u01b0\u1ee3ng l\u00f4ng chuy\u1ec3n gi\u1ea3m v\u00e0 ho\u1ea1t \u0111\u1ed9ng ti\u1ebft glycoprotein b\u1ecb r\u1ed1i lo\u1ea1n. Nh\u1eefng bi\u1ebfn \u0111\u1ed5i n\u00e0y cho th\u1ea5y m\u00f4i tr\u01b0\u1eddng trong \u1ed1ng d\u1eabn tr\u1ee9ng b\u1ecb \u1ea3nh h\u01b0\u1edfng theo h\u01b0\u1edbng b\u1ea5t l\u1ee3i, c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng v\u1eadn chuy\u1ec3n h\u1ee3p t\u1eed, c\u1ea3n tr\u1edf qu\u00e1 tr\u00ecnh th\u1ee5 tinh v\u00e0 ph\u00e1t tri\u1ec3n s\u1edbm c\u1ee7a ph\u00f4i.<\/p>\n<p style=\"text-align: justify;\">B\u00ean c\u1ea1nh \u0111\u00f3, nghi\u00ean c\u1ee9u c\u0169ng ghi nh\u1eadn s\u1ef1 thay \u0111\u1ed5i r\u00f5 r\u1ec7t v\u1ec1 s\u1ed1 l\u01b0\u1ee3ng t\u1ebf b\u00e0o th\u1ec3 v\u00e0ng nh\u1ecf (SLCs) v\u00e0 t\u1ebf b\u00e0o th\u1ec3 v\u00e0ng l\u1edbn (LLCs) theo t\u1eebng giai \u0111o\u1ea1n ph\u00e1t tri\u1ec3n c\u1ee7a th\u1ec3 v\u00e0ng. Giai \u0111o\u1ea1n \u0111\u1ea7u sau r\u1ee5ng tr\u1ee9ng, SLCs chi\u1ebfm \u01b0u th\u1ebf; \u0111\u1ebfn pha th\u1ec3 v\u00e0ng th\u00e0nh th\u1ee5c, LLCs t\u0103ng m\u1ea1nh v\u00e0 \u0111\u1ea1t c\u00e2n b\u1eb1ng t\u01b0\u01a1ng \u0111\u1ed1i v\u1edbi SLCs, t\u01b0\u01a1ng \u1ee9ng v\u1edbi giai \u0111o\u1ea1n ho\u1ea1t \u0111\u1ed9ng ti\u1ebft progesterone cao nh\u1ea5t. \u1ede pha tho\u00e1i h\u00f3a, s\u1ed1 l\u01b0\u1ee3ng LLCs gi\u1ea3m m\u1ea1nh trong khi SLCs c\u00f3 xu h\u01b0\u1edbng \u1ed5n \u0111\u1ecbnh h\u01a1n, ph\u1ea3n \u00e1nh s\u1ef1 kh\u00e1c bi\u1ec7t v\u1ec1 ch\u1ee9c n\u0103ng v\u00e0 m\u1ee9c \u0111\u1ed9 nh\u1ea1y c\u1ea3m v\u1edbi c\u00e1c t\u00edn hi\u1ec7u n\u1ed9i ti\u1ebft.<\/p>\n<p style=\"text-align: justify;\">Nh\u00ecn chung, nghi\u00ean c\u1ee9u \u0111\u00e3 cung c\u1ea5p b\u1eb1ng ch\u1ee9ng khoa h\u1ecdc v\u1ec1 s\u1ef1 bi\u1ebfn \u0111\u1ed5i \u0111\u1ed3ng th\u1eddi v\u1ec1 c\u1ea5u tr\u00fac v\u00e0 ch\u1ee9c n\u0103ng c\u1ee7a bu\u1ed3ng tr\u1ee9ng v\u00e0 \u1ed1ng d\u1eabn tr\u1ee9ng \u1edf b\u00f2 m\u1eafc b\u1ec7nh u nang bu\u1ed3ng tr\u1ee9ng. Ngo\u00e0i nguy\u00ean nh\u00e2n ch\u00ednh l\u00e0 hi\u1ec7n t\u01b0\u1ee3ng kh\u00f4ng r\u1ee5ng tr\u1ee9ng, nh\u1eefng thay \u0111\u1ed5i b\u1ea5t l\u1ee3i trong vi m\u00f4i tr\u01b0\u1eddng \u1ed1ng d\u1eabn tr\u1ee9ng c\u0169ng c\u00f3 th\u1ec3 l\u00e0 y\u1ebfu t\u1ed1 g\u00f3p ph\u1ea7n l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng sinh s\u1ea3n \u1edf b\u00f2 s\u1eefa. K\u1ebft qu\u1ea3 n\u00e0y c\u00f3 \u00fd ngh\u0129a quan tr\u1ecdng trong vi\u1ec7c \u0111\u1ecbnh h\u01b0\u1edbng ch\u1ea9n \u0111o\u00e1n, \u0111i\u1ec1u tr\u1ecb v\u00e0 c\u1ea3i thi\u1ec7n hi\u1ec7u qu\u1ea3 sinh s\u1ea3n trong ch\u0103n nu\u00f4i b\u00f2 s\u1eefa t\u1ea1i Vi\u1ec7t Nam.<\/p>\n<p>\u00a0<\/p>\n<table id=\"undefined\" class=\"imgEditor\" border=\"0\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" class=\"imgtelerik aligncenter\" src=\"https:\/\/file.vnua.edu.vn\/data\/0\/images\/2026\/05\/05\/host\/h1.png?w=680\" alt=\"\" \/><\/td>\n<\/tr>\n<tr class=\"alt_imgEditor\">\n<td>\u00a0<strong>H\u00ecnh<\/strong><strong>\u00a01.<\/strong>\u00a0\u0110\u1eb7c \u0111i\u1ec3m m\u00f4 h\u1ecdc c\u1ee7a ph\u1ec5u h\u1ee9ng tr\u1ee9ng b\u00f2 \u1edf pha nang tr\u1ee9ng, pha th\u1ec3 v\u00e0ng v\u00e0 trong tr\u01b0\u1eddng h\u1ee3p u nang bu\u1ed3ng tr\u1ee9ng, nhu\u1ed9m Hematoxylin \u2013 Eosin (H&amp;E)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div>\u00a0<\/div>\n<p style=\"text-align: justify;\">(A) H\u00ecnh \u1ea3nh t\u1ed5ng qu\u00e1t c\u1ee7a ph\u1ec5u h\u1ee9ng tr\u1ee9ng cho th\u1ea5y ni\u00eam m\u1ea1c g\u1ea5p n\u1ebfp nhi\u1ec1u, v\u1edbi c\u00e1c n\u1ebfp g\u1ea5p ch\u00ednh n\u1ed5i b\u1eadt (m\u0169i t\u00ean) v\u00e0 n\u1ebfp g\u1ea5p ph\u1ee5 (\u0111\u1ea7u m\u0169i t\u00ean). (B) Bi\u1ec3u m\u00f4 ph\u1ec5u h\u1ee9ng tr\u1ee9ng pha th\u1ec3 v\u00e0ng g\u1ed3m c\u00e1c t\u1ebf b\u00e0o c\u00f3 l\u00f4ng chuy\u1ec3n s\u1eabm m\u00e0u v\u1edbi l\u00f4ng chuy\u1ec3n r\u00f5 r\u00e0ng (m\u0169i t\u00ean tr\u1eafng), t\u1ebf b\u00e0o c\u00f3 l\u00f4ng chuy\u1ec3n s\u00e1ng m\u00e0u v\u1edbi l\u00f4ng chuy\u1ec3n th\u01b0a ho\u1eb7c kh\u00f4ng c\u00f3 (d\u1ea5u sao), v\u00e0 t\u1ebf b\u00e0o h\u00ecnh ch\u1ed1t (peg cells) nh\u1ecf, h\u1eb9p, k\u00e9o d\u00e0i (m\u0169i t\u00ean \u0111en). (C) Bi\u1ec3u m\u00f4 ph\u1ec5u h\u1ee9ng tr\u1ee9ng pha nang tr\u1ee9ng \u0111\u1eb7c tr\u01b0ng b\u1edfi s\u1ef1 \u01b0u th\u1ebf c\u1ee7a t\u1ebf b\u00e0o c\u00f3 l\u00f4ng chuy\u1ec3n (m\u0169i t\u00ean tr\u1eafng) v\u00e0 kh\u00f4ng ghi nh\u1eadn ho\u1ea1t \u0111\u1ed9ng ti\u1ebft r\u00f5 r\u1ec7t. L\u01b0u \u00fd s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a t\u1ebf b\u00e0o c\u00f3 l\u00f4ng chuy\u1ec3n s\u00e1ng m\u00e0u (d\u1ea5u sao). (D) Bi\u1ec3u m\u00f4 ph\u1ec5u h\u1ee9ng tr\u1ee9ng trong tr\u01b0\u1eddng h\u1ee3p u nang bu\u1ed3ng tr\u1ee9ng \u0111\u01b0\u1ee3c l\u00f3t b\u1edfi c\u00e1c t\u1ebf b\u00e0o bi\u1ec3u m\u00f4 tr\u1ee5 cao, nh\u00e2n n\u1eb1m c\u1ef1c \u0111\u00e1y v\u00e0 s\u1ed1 l\u01b0\u1ee3ng l\u00f4ng chuy\u1ec3n gi\u1ea3m r\u00f5 r\u1ec7t (m\u0169i t\u00ean tr\u1eafng). C\u00f3 hi\u1ec7n di\u1ec7n t\u1ebf b\u00e0o ti\u1ebft nh\u01b0ng kh\u00f4ng c\u00f3 c\u00e1c c\u1ea5u tr\u00fac chuy\u00ean bi\u1ec7t r\u00f5 \u1edf c\u1ef1c \u0111\u1ec9nh.<\/p>\n<p>\u00a0<\/p>\n<table id=\"undefined\" class=\"imgEditor\" border=\"0\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" class=\"imgtelerik aligncenter\" src=\"https:\/\/file.vnua.edu.vn\/data\/0\/images\/2026\/05\/05\/host\/h2.png?w=680\" alt=\"\" \/><\/td>\n<\/tr>\n<tr class=\"alt_imgEditor\">\n<td>\u00a0<strong>H\u00ecnh<\/strong><strong>\u00a02<\/strong>. Ph\u00e2n t\u00edch h\u00f3a m\u00f4 h\u1ecdc c\u1ee7a bi\u1ec3u m\u00f4 \u0111o\u1ea1n b\u00f3ng \u1ed1ng d\u1eabn tr\u1ee9ng pha nang tr\u1ee9ng, pha th\u1ec3 v\u00e0ng v\u00e0 trong tr\u01b0\u1eddng h\u1ee3p u nang bu\u1ed3ng tr\u1ee9ng<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\">(A) C\u00e1c t\u1ebf b\u00e0o ti\u1ebft pha th\u1ec3 v\u00e0ng cho ph\u1ea3n \u1ee9ng PAS d\u01b0\u01a1ng t\u00ednh m\u1ea1nh (m\u0169i t\u00ean \u0111en). (B) C\u00e1c t\u1ebf b\u00e0o ti\u1ebft pha nang tr\u1ee9ng cho ph\u1ea3n \u1ee9ng PAS d\u01b0\u01a1ng t\u00ednh m\u1ee9c trung b\u00ecnh (m\u0169i t\u00ean tr\u1eafng). (C) Trong tr\u01b0\u1eddng h\u1ee3p u nang bu\u1ed3ng tr\u1ee9ng, c\u00e1c t\u1ebf b\u00e0o ti\u1ebft bi\u1ec3u hi\u1ec7n ki\u1ec3u nhu\u1ed9m PAS kh\u00f4ng \u0111\u1ed3ng \u0111\u1ec1u, th\u01b0\u1eddng gi\u1ea3m c\u01b0\u1eddng \u0111\u1ed9 ho\u1eb7c ph\u00e2n b\u1ed1 kh\u00f4ng \u0111\u1ec1u (d\u1ea5u sao).<\/p>\n<p style=\"text-align: right;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<strong>TS. B\u00d9I V\u0102N D\u0168NG &#8211;<\/strong>\u00a0<strong>KHOA TH\u00da Y<\/strong><\/p>\n<p style=\"text-align: right;\"><strong>\u00a0BAN KHOA H\u1eccC V\u00c0 C\u00d4NG NGH\u1ec6<\/strong><\/p>","protected":false},"excerpt":{"rendered":"<p>B\u00f2 s\u1eefa Holstein\u2013Friesian l\u00e0 gi\u1ed1ng b\u00f2 c\u00f3 n\u0103ng su\u1ea5t s\u1eefa cao, tuy nhi\u00ean th\u01b0\u1eddng g\u1eb7p c\u00e1c r\u1ed1i lo\u1ea1n sinh s\u1ea3n, trong \u0111\u00f3 b\u1ec7nh u nang bu\u1ed3ng tr\u1ee9ng l\u00e0 m\u1ed9t trong nh\u1eefng nguy\u00ean nh\u00e2n quan tr\u1ecdng g\u00e2y gi\u1ea3m kh\u1ea3 n\u0103ng sinh s\u1ea3n. <\/p>\n","protected":false},"author":2,"featured_media":4412,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[197,1],"tags":[],"class_list":["post-4411","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-thong-bao","category-tin-tuc"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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