{"id":4417,"date":"2026-05-07T14:25:59","date_gmt":"2026-05-07T07:25:59","guid":{"rendered":"http:\/\/khcn185.vnua.edu.vn\/?p=4417"},"modified":"2026-05-07T14:26:37","modified_gmt":"2026-05-07T07:26:37","slug":"mot-so-dac-diem-dich-te-va-de-xuat-giai-phap-phong-chong-virus-tembusu-tren-vit-tai-viet-nam","status":"publish","type":"post","link":"http:\/\/khcn185.vnua.edu.vn\/?p=4417","title":{"rendered":"M\u1ed9t s\u1ed1 \u0111\u1eb7c \u0111i\u1ec3m d\u1ecbch t\u1ec5 v\u00e0 \u0111\u1ec1 xu\u1ea5t gi\u1ea3i..."},"content":{"rendered":"\n\n

Nh\u1eb1m g\u00f3p ph\u1ea7n n\u00e2ng cao hi\u1ec7u qu\u1ea3 ph\u00f2ng ch\u1ed1ng d\u1ecbch b\u1ec7nh tr\u00ean \u0111\u00e0n th\u1ee7y c\u1ea7m, nh\u00f3m nghi\u00ean c\u1ee9u t\u1ea1i H\u1ecdc vi\u1ec7n N\u00f4ng nghi\u1ec7p Vi\u1ec7t Nam \u0111\u00e3 tri\u1ec3n khai \u0111\u1ec1 t\u00e0i nghi\u00ean c\u1ee9u c\u1ea5p B\u1ed9 N\u00f4ng nghi\u1ec7p v\u00e0 M\u00f4i tr\u01b0\u1eddng v\u1ec1 b\u1ec7nh do virus Tembusu (TMUV) g\u00e2y ra \u1edf v\u1ecbt nu\u00f4i t\u1ea1i Vi\u1ec7t Nam. \u0110\u1ec1 t\u00e0i t\u1eadp trung v\u00e0o ba n\u1ed9i dung ch\u00ednh g\u1ed3m: nghi\u00ean c\u1ee9u \u0111\u1eb7c \u0111i\u1ec3m d\u1ecbch t\u1ec5 h\u1ecdc c\u1ee7a b\u1ec7nh do virus Tembusu tr\u00ean \u0111\u00e0n v\u1ecbt nu\u00f4i; ph\u00e2n l\u1eadp virus v\u00e0 x\u00e1c \u0111\u1ecbnh c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m b\u1ec7nh l\u00fd; \u0111\u1ed3ng th\u1eddi \u0111\u1ec1 xu\u1ea5t gi\u1ea3i ph\u00e1p ph\u00f2ng ch\u1ed1ng b\u1ec7nh ph\u00f9 h\u1ee3p v\u1edbi \u0111i\u1ec1u ki\u1ec7n ch\u0103n nu\u00f4i t\u1ea1i Vi\u1ec7t Nam.<\/p>\n

Trong qu\u00e1 tr\u00ecnh th\u1ef1c hi\u1ec7n, nh\u00f3m nghi\u00ean c\u1ee9u \u0111\u00e3 x\u00e2y d\u1ef1ng v\u00e0 ho\u00e0n thi\u1ec7n phi\u1ebfu \u0111i\u1ec1u tra ph\u1ee5c v\u1ee5 ph\u00e2n t\u00edch d\u1ecbch t\u1ec5 h\u1ecdc m\u00f4 t\u1ea3 c\u0169ng nh\u01b0 \u0111\u00e1nh gi\u00e1 c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 ph\u00e1t sinh d\u1ecbch b\u1ec7nh. M\u1eabu b\u1ec7nh ph\u1ea9m \u0111\u01b0\u1ee3c thu th\u1eadp theo quy chu\u1ea9n k\u1ef9 thu\u1eadt qu\u1ed1c gia t\u1ea1i 8 t\u1ec9nh, th\u00e0nh ph\u1ed1 \u0111\u1ea1i di\u1ec7n cho nhi\u1ec1u v\u00f9ng sinh th\u00e1i kh\u00e1c nhau g\u1ed3m Ph\u00fa Th\u1ecd, L\u1ea1ng S\u01a1n, Th\u00e1i B\u00ecnh, Ngh\u1ec7 An, Qu\u1ea3ng Nam, \u0110\u1eafk L\u1eafk, B\u00e0 R\u1ecba \u2013 V\u0169ng T\u00e0u v\u00e0 H\u1eadu Giang. C\u00e1c m\u1eabu \u0111\u01b0\u1ee3c x\u00e9t nghi\u1ec7m b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p RT-LAMP nh\u1eb1m ph\u00e1t hi\u1ec7n virus Tembusu, \u0111\u1ed3ng th\u1eddi k\u1ef9 thu\u1eadt RT-PCR \u0111\u01b0\u1ee3c t\u1ed1i \u01b0u h\u00f3a \u0111\u1ec3 ph\u1ee5c v\u1ee5 nh\u00e2n gen v\u00e0 gi\u1ea3i tr\u00ecnh t\u1ef1 virus. Tr\u00ean c\u01a1 s\u1edf c\u00e1c k\u1ebft qu\u1ea3 ph\u00e2n t\u00edch, nh\u00f3m nghi\u00ean c\u1ee9u \u0111\u00e3 x\u00e2y d\u1ef1ng d\u1ef1 th\u1ea3o ti\u00eau chu\u1ea9n ch\u1ea9n \u0111o\u00e1n b\u1ec7nh \u0111\u1ed9ng v\u1eadt ph\u1ee5c v\u1ee5 c\u00f4ng t\u00e1c chuy\u00ean m\u00f4n.<\/p>\n

\"\"
K\u1ebft qu\u1ea3 s\u1eed d\u1ee5ng ph\u01b0\u01a1ng ph\u00e1p RT-LAMP \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n virus Tembusu<\/figcaption><\/figure>\n


K\u1ebft qu\u1ea3 nghi\u00ean c\u1ee9u cho th\u1ea5y virus Tembusu \u0111\u00e3 xu\u1ea5t hi\u1ec7n t\u1ea1i t\u1ea5t c\u1ea3 c\u00e1c t\u1ec9nh \u0111\u01b0\u1ee3c \u0111i\u1ec1u tra v\u1edbi t\u1ef7 l\u1ec7 l\u01b0u h\u00e0nh trung b\u00ecnh \u0111\u1ea1t 7,95%. Nh\u00f3m v\u1ecbt d\u01b0\u1edbi 20 tu\u1ea7n tu\u1ed5i c\u00f3 t\u1ef7 l\u1ec7 nhi\u1ec5m cao nh\u1ea5t, dao \u0111\u1ed9ng t\u1eeb 8,39% \u0111\u1ebfn 8,62%. Virus \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n nhi\u1ec1u \u1edf c\u00e1c trang tr\u1ea1i quy m\u00f4 v\u1eeba v\u00e0 xu\u1ea5t hi\u1ec7n \u1edf c\u1ea3 \u0111\u00e0n v\u1ecbt nu\u00f4i h\u01b0\u1edbng th\u1ecbt l\u1eabn h\u01b0\u1edbng tr\u1ee9ng. \u0110\u00e1ng ch\u00fa \u00fd, t\u1ef7 l\u1ec7 l\u01b0u h\u00e0nh virus \u1edf gi\u1ed1ng v\u1ecbt n\u1ed9i cao h\u01a1n so v\u1edbi gi\u1ed1ng v\u1ecbt nh\u1eadp ngo\u1ea1i. Th\u00f4ng qua ph\u00e2n t\u00edch tr\u00ecnh t\u1ef1 c\u00e1c gen E, PrM v\u00e0 NS5, nghi\u00ean c\u1ee9u x\u00e1c \u0111\u1ecbnh c\u00e1c ch\u1ee7ng virus Tembusu l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam c\u00f3 quan h\u1ec7 g\u1ea7n v\u1edbi c\u00e1c ch\u1ee7ng \u0111ang l\u01b0u h\u00e0nh t\u1ea1i Th\u00e1i Lan v\u00e0 Trung Qu\u1ed1c, thu\u1ed9c Clade 2.1. V\u1ecbt m\u1eafc b\u1ec7nh th\u01b0\u1eddng bi\u1ec3u hi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 s\u1ed1t, ti\u00eau ch\u1ea3y ph\u00e2n xanh, gi\u1ea3m v\u1eadn \u0111\u1ed9ng, x\u00f9 l\u00f4ng, co gi\u1eadt v\u00e0 gi\u1ea3m s\u1ea3n l\u01b0\u1ee3ng tr\u1ee9ng. B\u1ec7nh t\u00edch \u0111i\u1ec3n h\u00ecnh bao g\u1ed3m tim ho\u1ea1i t\u1eed, gan v\u00e0 l\u00e1ch s\u01b0ng, xu\u1ea5t huy\u1ebft \u1edf th\u1eadn v\u00e0 bu\u1ed3ng tr\u1ee9ng.<\/span><\/p>\n

\"\"
Bi\u1ec3u hi\u1ec7n c\u1ee7a v\u1ecbt m\u1eafc b\u1ec7nh do virus Tembusu g\u00e2y ra<\/figcaption><\/figure>\n


Ngo\u00e0i ra, nghi\u00ean c\u1ee9u c\u0169ng ghi nh\u1eadn nhi\u1ec1u tr\u01b0\u1eddng h\u1ee3p \u0111\u1ed3ng nhi\u1ec5m v\u1edbi c\u00e1c t\u00e1c nh\u00e2n g\u00e2y b\u1ec7nh kh\u00e1c nh\u01b0 virus d\u1ecbch t\u1ea3 v\u1ecbt v\u00e0 vi khu\u1ea9n <\/span>E. coli<\/em>, l\u00e0m cho tri\u1ec7u ch\u1ee9ng v\u00e0 b\u1ec7nh t\u00edch tr\u1edf n\u00ean nghi\u00eam tr\u1ecdng h\u01a1n. M\u1ed9t trong nh\u1eefng k\u1ebft qu\u1ea3 n\u1ed5i b\u1eadt c\u1ee7a \u0111\u1ec1 t\u00e0i l\u00e0 \u0111\u00e3 ph\u00e2n l\u1eadp th\u00e0nh c\u00f4ng 3 ch\u1ee7ng virus Tembusu c\u00f3 ti\u1ec1m n\u0103ng s\u1eed d\u1ee5ng trong nghi\u00ean c\u1ee9u v\u00e0 s\u1ea3n xu\u1ea5t v\u1eafc xin. C\u00e1c ch\u1ee7ng virus n\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 \u0111\u1eb7c t\u00ednh sinh h\u1ecdc, kh\u1ea3 n\u0103ng th\u00edch nghi tr\u00ean ph\u00f4i v\u1ecbt v\u00e0 x\u00e1c \u0111\u1ecbnh c\u00e1c ch\u1ec9 s\u1ed1 \u0111\u1ed9c l\u1ef1c, kh\u1ea3 n\u0103ng g\u00e2y nhi\u1ec5m. \u0110\u1ed3ng th\u1eddi, nh\u00f3m nghi\u00ean c\u1ee9u \u0111\u00e3 c\u00f4ng b\u1ed1 5 tr\u00ecnh t\u1ef1 gen virus Tembusu tr\u00ean GenBank, g\u00f3p ph\u1ea7n b\u1ed5 sung ngu\u1ed3n d\u1eef li\u1ec7u khoa h\u1ecdc ph\u1ee5c v\u1ee5 nghi\u00ean c\u1ee9u trong n\u01b0\u1edbc v\u00e0 qu\u1ed1c t\u1ebf.<\/span><\/p>\n

\"\"
K\u1ebft qu\u1ea3 x\u00e1c \u0111\u1ecbnh Epitop kh\u00e1ng nguy\u00ean c\u1ee7a virus Tembusu ph\u00e2n l\u1eadp \u0111\u01b0\u1ee3c<\/figcaption><\/figure>\n


T\u1eeb c\u00e1c k\u1ebft qu\u1ea3 \u0111\u1ea1t \u0111\u01b0\u1ee3c, nh\u00f3m nghi\u00ean c\u1ee9u \u0111\u1ec1 xu\u1ea5t nhi\u1ec1u gi\u1ea3i ph\u00e1p ph\u00f2ng ch\u1ed1ng b\u1ec7nh hi\u1ec7u qu\u1ea3 nh\u01b0 ph\u00e1t hi\u1ec7n s\u1edbm b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p RT-LAMP, x\u00e1c nh\u1eadn b\u1eb1ng RT-PCR k\u1ebft h\u1ee3p gi\u1ea3i tr\u00ecnh t\u1ef1 gen; th\u1ef1c hi\u1ec7n nghi\u00eam c\u00e1c bi\u1ec7n ph\u00e1p an to\u00e0n sinh h\u1ecdc; c\u00e1ch ly v\u1ecbt b\u1ec7nh v\u00e0 ki\u1ec3m so\u00e1t c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 t\u1ea1i trang tr\u1ea1i. Nghi\u00ean c\u1ee9u c\u0169ng khuy\u1ebfn ngh\u1ecb \u01b0u ti\u00ean s\u1eed d\u1ee5ng c\u00e1c lo\u1ea1i v\u1eafc xin c\u00f3 ch\u1ee7ng t\u01b0\u01a1ng \u0111\u1ed3ng cao v\u1edbi virus th\u1ef1c \u0111\u1ecba \u0111ang l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam nh\u1eb1m n\u00e2ng cao hi\u1ec7u qu\u1ea3 b\u1ea3o h\u1ed9 cho \u0111\u00e0n v\u1ecbt nu\u00f4i.<\/span><\/p>\n

K\u00ea\u0301t qua\u0309 trong nghi\u00ean c\u01b0\u0301u \u0111a\u0303 \u0111\u01b0\u01a1\u0323c \u0111\u0103ng ta\u0309i tr\u00ean T\u1ea1p ch\u00ed Khoa h\u1ecdc k\u1ef9 thu\u1eadt Th\u00fa y t\u1eadp XXXII, s\u1ed1 7 \u2013 2025.<\/p>\n

TS. \u0110\u1eb7ng H\u1eefu Anh – Khoa Th\u00fa y<\/strong><\/p>\n

Ban Khoa ho\u0323c C\u00f4ng ngh\u00ea\u0323<\/strong><\/p>","protected":false},"excerpt":{"rendered":"

Nh\u1eb1m g\u00f3p ph\u1ea7n n\u00e2ng cao hi\u1ec7u qu\u1ea3 ph\u00f2ng ch\u1ed1ng d\u1ecbch b\u1ec7nh tr\u00ean \u0111\u00e0n th\u1ee7y c\u1ea7m, nh\u00f3m nghi\u00ean c\u1ee9u t\u1ea1i H\u1ecdc vi\u1ec7n N\u00f4ng nghi\u1ec7p Vi\u1ec7t Nam \u0111\u00e3 tri\u1ec3n khai \u0111\u1ec1 t\u00e0i nghi\u00ean c\u1ee9u c\u1ea5p B\u1ed9 N\u00f4ng nghi\u1ec7p v\u00e0 M\u00f4i tr\u01b0\u1eddng v\u1ec1 b\u1ec7nh do virus Tembusu (TMUV) g\u00e2y ra \u1edf v\u1ecbt nu\u00f4i t\u1ea1i Vi\u1ec7t Nam.<\/p>\n","protected":false},"author":2,"featured_media":4420,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4417","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"yoast_head":"\nM\u1ed9t s\u1ed1 \u0111\u1eb7c \u0111i\u1ec3m d\u1ecbch t\u1ec5 v\u00e0 \u0111\u1ec1 xu\u1ea5t gi\u1ea3i ph\u00e1p ph\u00f2ng ch\u1ed1ng virus Tembusu tr\u00ean v\u1ecbt t\u1ea1i Vi\u1ec7t Nam - 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